Brand Name(s): Miebo^®

WHY is this medicine prescribed?

Perfluorohexyloctane ophthalmic solution is used to treat signs and symptoms of dry eye disease (a condition where tears aren't able to provide adequate moisture for your eyes). Perfluorohexyloctane is in a class of medications called semifluorinated alkanes. It works by providing a film layer on the eye to prevent tears and moisture from evaporating.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

HOW should this medicine be used?

Perfluorohexyloctane ophthalmic comes as a solution (liquid) to place into the eye. It is usually used four times a day. Contact lenses should be removed before using the eye drops and kept out for at least 30 minutes after using perfluorohexyloctane. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use perfluorohexyloctane exactly as directed. Do not use more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Perfluorohexyloctane ophthalmic solution controls dry eye disease but does not cure it. Continue to take perfluorohexyloctane even if your symptoms improve. Do not stop using perfluorohexyloctane without talking to your doctor.

To use the perfluorohexyloctane eye drops, follow these steps:

1. wash hands
2. remove contact lenses
3. remove the cap from the eye drop bottle
4. holding bottle upright, gently squeeze the bottle
5. while squeezing the bottle, turn bottle upside down and stop squeezing
6. keeping the bottle upside down, place the bottle above your eye and squeeze 1 drop into affected eye
7. repeat the above steps for the second eye, if needed

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

What SPECIAL PRECAUTIONS should I follow?

Before using perfluorohexyloctane ophthalmic solution,

• tell your doctor and pharmacist if you are allergic to perfluorohexyloctane, any other medications, or any of the ingredients in perfluorohexyloctane ophthalmic solution. Ask your pharmacist for a list of the ingredients.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using perfluorohexyloctane, call your doctor.

What should I do IF I FORGET to take a dose?

Place the missed dose in your eye(s) as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply extra eye drops to make up for a missed dose.

What SIDE EFFECTS can this medicine cause?

Perfluorohexyloctane may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• blurred vision
• red eyes

Perfluorohexyloctane ophthalmic solution may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I do in case of OVERDOSE?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS^® Patient Medication Information™. © Copyright, 2024. The American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: November 15, 2023.